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PROMIS Domains
PROMIS® Measures for Adults
PROMIS Domains and Measures
PROMIS includes multiple types of measures of physical, mental, and social health:
- Computer adaptive tests (CATs)
- Screen-to-CATs
- Short forms (usually 4-8 items)
- Profiles (collection of short forms or computer adaptive tests)
Read about each PROMIS measure type.
The following tables list all PROMIS domains and measures.
| Domain | Definition | CAT (# Items in Bank) | Screen-to-CAT (# Items in Bank) | Short Form or Scale (# Items) |
|---|---|---|---|---|
| Ability to Participate in Social Roles and Activities | Perceived ability to perform one’s usual social roles and activities. | ✓ | ✓ | ✓ |
| Cognitive Function | Mental acuity, concentration, verbal and nonverbal memory, verbal fluency, and perceived changes in these cognitive functions. The extent to which cognitive impairments interfere with daily functioning, whether other people observe cognitive impairments, and the impact of cognitive dysfunction on quality of life are also assessed. | ✓ | ✓ | ✓ |
| Emotional Distress – Anxiety | Fear (fearfulness, panic), anxious misery (worry, dread), hyperarousal (tension, nervousness, restlessness), and somatic symptoms related to arousal (racing heart, dizziness). | ✓ | ✓ | ✓ |
| Emotional Distress – Depression | Negative mood (sadness, guilt), views of self (self-criticism, worthlessness), and social cognition (loneliness, interpersonal alienation), as well as decreased positive affect and engagement (loss of interest, meaning, and purpose). | ✓ | ✓ | ✓ |
| Fatigue | Range of symptoms, from mild subjective feelings of tiredness to an overwhelming, debilitating, and sustained sense of exhaustion that likely decreases one’s ability to execute daily activities and function normally in family or social roles. | ✓ | ✓ | ✓ |
| Pain Intensity | How much a person hurts. | ✓ | ||
| Pain Interference | Consequences of pain on relevant aspects of one’s life. This includes the extent to which pain hinders engagement with social, cognitive, emotional, physical, and recreational activities. | ✓ | ✓ | ✓ |
| Physical Function | Self-reported capability rather than actual performance of physical activities. This includes the functioning of one’s upper extremities (dexterity), lower extremities (walking or mobility), and central regions (neck, back), as well as instrumental activities of daily living, such as running errands. | ✓ | ✓ | ✓ |
| Sleep Disturbance | Perceptions of sleep quality, sleep depth, and restoration associated with sleep. | ✓ | ✓ | ✓ |
| Sleep-Related Impairment | Perceptions of alertness, sleepiness, and tiredness during usual waking hours, and the perceived functional impairments during wakefulness associated with sleep problems or impaired alertness. | ✓ | ✓ | ✓ |
s This measure is a scale (items are not a subset from an item bank and the measure produces a score).
| Domain | Definition | CAT
(# Items in Bank) | Screen-to-CAT
(# Items in Bank) | Short Form or Scale
(# Items) |
|---|---|---|---|---|
| Dyspnea – Activity Motivation | An adult’s relative dispositional tendency or preference toward being active or sedentary. | ✓ | ||
| Dyspnea – Activity Requirements | Impact of an adult’s environment on their physical activity levels and external activity demands on an adult, such as work outside the home and aspects of the home environment (e.g., stairs). | ✓ | ||
| Dyspnea – Airborne Exposure | Environmental factors related to dyspnea, including exposure to airborne allergens, pollutants and smoke, and whether or not an adult is exposed to airborne factors in their environment that could impact their shortness of breath. | ✓ | ||
| Dyspnea – Assistive Devices | Availability and use of assistive devices (e.g., cane, grab bar, or oxygen) and whether or not an individual uses such devices. | ✓ | ||
| Dyspnea – Characteristics | Various descriptive aspects of a person’s experience of dyspnea, including quantitative and qualitative descriptions of the severity and intensity of shortness of breath as well as its frequency and duration. | ✓ | ||
| Dyspnea – Emotional Response | Emotions experienced related to dyspnea, including embarrassment, fear and worry, and how individuals may react emotionally to their shortness of breath. | ✓ | ||
| Dyspnea – Functional Limitations | Impact of dyspnea (i.e. shortness of breath or difficulty breathing) on an adult’s ability to function while performing specific daily activities (e.g., dressing oneself without help, preparing meals, walking up 20 stairs). | ✓ | ✓ | |
| Dyspnea – Task Avoidance | An adult’s decision to stop engaging in certain activities when the breathing discomfort associated with continuing the activity can no longer be tolerated. | ✓ | ||
| Dyspnea – Time Extension | Whether there has been a meaningful increase or decrease in the duration of time needed by an adult to perform a given task in the past 7 days (compared to 3 months ago) due to shortness of breath. | ✓ | ||
| Dyspnea – Severity | Severity of shortness of breath or difficulty breathing an adult experiences in response to various specific activities (the same activities assessed in Dyspnea Functional Limitations). | ✓ | ✓ | |
| Gastrointestinal – Belly Pain | Frequency, intensity, and quality of belly pain, as well as the associated bothersomeness and interference with daily activities that may result from belly pain. | ✓ | ||
| Gastrointestinal – Bowel Incontinence | Frequency of bowel incontinence, soiling, and gas incontinence (i.e., stool leakage while passing gas). | ✓ | ||
| Gastrointestinal – Constipation | Frequency and intensity of constipation-related symptoms (e.g., incomplete evacuation, rectal pain, straining, hard stools, manual extraction of stool) and the associated bothersomeness of these symptoms. | ✓ | ||
| Gastrointestinal – Diarrhea | Frequency, bothersomeness, and impact of bowel urgency. | ✓ | ||
| Gastrointestinal – Disrupted Swallowing | Frequency of various swallowing-related symptoms (e.g., difficulty swallowing solid foods, soft foods, liquids, and pills; throat/chest pain; the sensation of food being stuck in the throat/chest). | ✓ | ||
| Gastrointestinal – Gas and Bloating | Frequency, intensity, and severity of bloating (i.e., feeling pressure or fullness), bloating appearance (i.e., belly swollen or larger than usual size), flatulence (i.e., passing gas), and abdominal sounds (i.e., gurgling or rumbling), as well as the predictability, bothersomeness, and interference with daily activities that result from these symptoms. | ✓ | ||
| Gastrointestinal – Gastroesophageal Reflux | Symptoms associated with stomach contents leaking backwards from the stomach into the esophagus (e.g., the frequency of regurgitation, the experience of burning or a lump in the throat, burping, hiccupping, and excessive saliva production), as well as the bothersomeness that results from these symptoms. | ✓ | ||
| Gastrointestinal – Nausea and Vomiting | Frequency of vomiting, nausea, and poor appetite, as well as the predictability of nausea. | ✓ | ||
| Itch – Activity & Clothing | Activity and clothing related quality of life impairment from itch (pruritis). | ✓ | ✓ | |
| Itch – Interference | General issues related to quality of life impairment from itch (pruritis). | ✓ | ✓ | |
| Itch – Mood & Sleep | Mood and sleep related quality of life impairment from itch (pruritis). | ✓ | ✓ | |
| Itch – Quality | Assesses the subjective description of the sensation of itch with a checklist. | ✓ | ||
| Itch – Scratching Behavior | Quality of life impairment from scratching behavior and the physical manifestations of itch (pruritis). | ✓ | ||
| Itch – Severity | Characteristics of itch, including intensity, frequency, and time of occurrence. | ✓ | ||
| Itch – Triggers | Assesses the subjective description of the triggers of itch with a checklist. | ✓ | ||
| Pain Behavior | Behaviors that typically indicate to others that an individual is experiencing pain. These actions or reactions can be verbal or nonverbal, and involuntary or deliberate. | ✓ | ✓ | |
| Pain Quality – Neuropathic Pain | Caused by damage to the peripheral somatosensory nervous system, part of the nervous system involved in bodily feelings. This damage can be caused by an abnormality, trauma or disease. | ✓ | ||
| Pain Quality – Nociceptive Pain | Caused by stimulation of peripheral nerve fibers (nociceptors) in the context of a normally functioning somatosensory nervous system. | ✓ | ||
| Physical Function – Mobility | Activities of physical mobility such as getting out of bed or a chair to activities such as running. | ✓ | ||
| Physical Function – Upper Extremity | Activities that require use of the upper extremity including shoulder, arm, and hand activities. Examples include writing, using buttons, or opening containers. | ✓ | ✓ | ✓ |
| Physical Function for Samples with Mobility Aid Users | For samples that may include individuals who use mobility aids such as wheelchairs. | ✓ | ✓ | |
| Sexual Function and Satisfaction – Anal Discomfort with Sexual Activity (for Sexually Active People) | Anal irritation, pain, or bleeding during or after anal sex. | ✓ | ||
| Sexual Function and Satisfaction – Bother Regarding Sexual Function | The extent to which people were bothered by aspects of sexual functioning. | Female: (9p) Male (6p) | ||
| Sexual Function and Satisfaction – Erectile Function (for Sexually Active Men) | Ability to achieve and maintain an erection for sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Factors Interfering with Sexual Satisfaction | Perception of the degree to which various factors affect satisfaction with sex life. These factors include symptoms of disease and side effects from treatment and other issues that have been identified by participants. | ✓ | ||
| Sexual Function and Satisfaction – Interest in Sexual Activity | Conscious awareness of wanting to engage in sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Oral Discomfort with Sexual Activity (for Sexually Active People) | The degree of physical discomfort in the mouth, including pain and/or irritation, experienced with sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Oral Dryness with Sexual Activity (for Sexually Active People) | The lack of saliva in the mouth experienced with sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Orgasm – Ability (for Sexually Active People) | The degree to which the person has experienced a satisfying climax. | ✓ | ||
| Sexual Function and Satisfaction – Orgasm – Pleasure (for Sexually Active People) | How pleasurable or satisfying the person’s orgasms have felt. | ✓ | ||
| Sexual Function and Satisfaction – Satisfaction with Sex Life | An overall evaluation of his or her sex life. No limitation is placed on what the person includes in his or her definition of “sex life.” | ✓ | ||
| Sexual Function and Satisfaction – Screeners | Asks about sex (gender), whether people are in a relationship that could involve sexual activity, and whether they have had any type of sexual activity with a partner in the past 30 days. | ✓ | ||
| Sexual Function and Satisfaction – Sexual Activities | Self-reported frequency of engaging in specific intimate or sexual behaviors, either alone or with a partner. | Female: ✓(14p) Male: ✓ (13p) | ||
| Sexual Function and Satisfaction – Therapeutic Aids for Sexual Activity | Use of hormones, personal lubrications, medications, or devices intended to allow for or improve sexual function. | Female: ✓(3p) Male: ✓ (5p) | ||
| Sexual Function and Satisfaction – Vaginal Discomfort with Sexual Activity (for Sexually Active Women) | Physical discomfort of the vagina during and immediately following sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Vaginal Lubrication for Sexual Activity (for Sexually Active Women) | Wetness or dryness of the vagina during sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Vulvar Discomfort with Sexual Activity – Clitoral (for Sexually Active Women) | The degree of physical discomfort, including pain, of the clitoris experienced with sexual activity. | ✓ | ||
| Sexual Function and Satisfaction – Vulvar Discomfort with Sexual Activity – Labial (for Sexually Active Women) | The degree of physical discomfort, including pain, of the labia experienced with sexual activity. | ✓ |
p This measure is an item pool. An item pool is a collection of items that are not scored.
s This measure is a scale (items are not a subset from an item bank and the measure produces a score).
c This measure is a checklist. Responses are usually yes/no. It does not produce a score.
| Domain | Definition | CAT (# Items in Bank) | Short Form or Scale
(# Items) |
|---|---|---|---|
| Alcohol – Alcohol Use | Drinking patterns, cue-based drinking, cravings to drink, and efforts to control drinking that indicate problematic drinking, particularly at the high end of the severity continuum. | ✓ | ✓ |
| Alcohol – Negative Consequences | Negative personal outcomes of alcohol use over the past 30 days. These items cover physical, mental, and social consequences of drinking. | ✓ | ✓ |
| Alcohol – Negative Expectancies | General attitudes about negative outcomes of alcohol use. These items cover physical, mental, and social negative expectancies of drinking. | ✓ | ✓ |
| Alcohol – Positive Consequences | Positive personal outcomes of alcohol use over the past 30 days. These items cover physical, mental, and social consequences of drinking. | ✓ | ✓ |
| Alcohol – Positive Expectancies | General attitudes about positive outcomes of alcohol use. These items cover physical, mental, and social positive expectancies of drinking. | ✓ | ✓ |
| Cognitive Function – Abilities | Patient-perceived functional abilities with regard to cognitive tasks, including the perception that one’s cognitive ability with regard to the domain of inquiry (e.g., concentration, memory) has not changed. | ✓ | ✓ |
| Emotional Distress – Anger | Angry mood (irritability, frustration), negative social cognitions (interpersonal sensitivity, envy, disagreeableness), and efforts to control anger. | ✓ | ✓ |
| General Life Satisfaction | One’s cognitive evaluation of life experiences and whether one likes his/her life or not. | ✓ | ✓ |
| Healthcare Access Satisfaction | One’s ability to get medical services, when needed (specific to adults with type 2 diabetes mellitus). | ✓ | ✓ |
| Illness Burden | The impact that a chronic medical condition(s) has on one’s independent living, the ability to work (including working at home), social activities, and relationships. | ✓ | ✓ |
| Meaning and Purpose | A sense that life has purpose and there are good reasons for living, including hopefulness, optimism, goal-directedness, and feelings that one’s life is worthy. | ✓ | ✓ |
| Medication Adherence | Behaviors related to taking oral medication as prescribed by a doctor. | ✓ | |
| Positive Affect | Feelings that reflect a level of pleasurable engagement with the environment, such as happiness, joy, excitement, enthusiasm, and contentment. | ✓ | ✓ |
| Positive Attitudes Toward Complementary and Integrative Medicine | An individual’s perception of the effectiveness of complementary and integrative medicine and the use of complementary and integrative medicine when seeking treatment. The items include level of preference for natural remedies and complementary and integrative medicine relative to conventional medicine. | ✓ | |
| Positive Outlook | Positive views of oneself, satisfaction with current life, and expectations for the future. The items capture self-worth, self-confidence, and levels of satisfaction with life circumstances as well as optimistic views of the future. | ✓ | ✓ |
| Positive Treatment Expectations | Patients’ expectations about their treatment including the degree of confidence in treatment effectiveness, expectations of the benefit, perceived credibility of treatment concepts, and congruence of treatment with beliefs and attitudes about health. | ✓ | ✓ |
| Psychosocial Illness Impact – Negative | Direct negative psychosocial effect of cancer, distinct from general emotional distress. | ✓ | ✓ |
| Psychosocial Illness Impact – Positive | Positive psychosocial (emotional and social) outcomes of illness, previously conceptualized in various ways including post-traumatic growth, benefit-finding, and meaning making. | ✓ | ✓ |
| Self-Efficacy – General | Confidence in ability to deal effectively with a variety of stressful situations. | ✓ | ✓ |
| Self-Efficacy for Managing Chronic Conditions – Manage Daily Activities | Confidence in performing various activities of daily living (ADLs) without assistance. Items also assess exercise, sexual activities and managing activities in challenging situations (travelling, bad weather). | ✓ | ✓ |
| Self-Efficacy for Managing Chronic Conditions – Manage Emotions | Confidence to manage/control symptoms of anxiety, depression, helplessness, discouragement, frustration, disappointment and anger. | ✓ | ✓ |
| Self-Efficacy for Managing Chronic Conditions – Manage Meds/Treatment | Confidence in managing medication schedules of different complexity. Managing medication and other treatments in challenging situations such as when travelling, when running out of medication, and when adverse effects are encountered. | ✓ | ✓ |
| Self-Efficacy for Managing Chronic Conditions – Manage Social Interactions | Confidence in participating in social activities and getting help when necessary. Managing communication with others about their medical condition, including communication with health professionals. | ✓ | ✓ |
| Self-Efficacy for Managing Chronic Conditions – Manage Symptoms | Confidence to manage/control their symptoms, to manage their symptoms in different settings and to keep symptoms from interfering with work, sleep, relationships or recreational activities. | ✓ | ✓ |
| Smoking – Coping Expectancies | Using smoking as a way to cope with various types of negative affect, affective consequences of not smoking, and the extent to which negative affect triggers smoking. | All Smokers: ✓(11) Daily Smokers: ✓(15) Nondaily Smokers: ✓(18) | All Smokers: ✓(4) Daily Smokers: ✓(4) Nondaily Smokers: ✓(4) |
| Smoking – Emotional/Sensory Expectancies | Improved cognitive abilities (e.g., concentration), positive affective states (e.g., relaxation, contentment), and enjoyable sensorimotor sensations (e.g., from the ritual of lighting up a cigarette, smelling the cigarette, inhaling the smoke) that are experienced as a result of smoking. | All Smokers: ✓(15) Daily Smokers: ✓(16) Nondaily Smokers: ✓(17) | All Smokers: ✓(6) Daily Smokers: ✓(6) Nondaily Smokers: ✓(6) |
| Smoking – Negative Health Expectancies | Health-related outcome expectancies of smoking (e.g., Smoking gives me a headache) and quitting (e.g., if I quit smoking I will breathe easier), and emotions such as worry (e.g., about developing serious health problems in the future). | All Smokers: ✓(12) Daily Smokers: ✓(19) Nondaily Smokers: ✓(18) | All Smokers: ✓(6) Daily Smokers: ✓(6) Nondaily Smokers: ✓(6) |
| Smoking – Negative Psychosocial Expectancies | Friend and family disapproval (e.g., if I quit smoking my friends will respect me more), self-disapproval (e.g., I get upset when I think about my smoking), and internalization of social norms (e.g., I feel uncomfortable smoking around kids). | All Smokers: ✓(14) Daily Smokers: ✓(20) Nondaily Smokers: ✓(15) | All Smokers: ✓(6) Daily Smokers: ✓(6) Nondaily Smokers: ✓(6) |
| Smoking – Nicotine Dependence | Tolerance, craving, withdrawal severity, temptations to smoke, and smoking as a behavioral priority. | All Smokers: ✓(20) Daily Smokers: ✓(27) Nondaily Smokers: ✓(27) | All Smokers: ✓(4, 8) Daily Smokers: ✓(4, 8) Nondaily Smokers: ✓(4, 8) |
| Smoking – Social Motivations | Beliefs that: (a) smoking makes social situations more comfortable or enjoyable; (b) smoking provides a sense of camaraderie and belonging; (c) quitting smoking can negatively impact existing relationships with smokers; and (d) being in certain social situations increases smoking or the temptation to smoke. | All Smokers: ✓(7) Daily Smokers: ✓(12) Nondaily Smokers: ✓(12) | All Smokers: ✓(4) Daily Smokers: ✓(4) Nondaily Smokers: ✓(4) |
| Spirituality | Spiritual beliefs and experiences including receiving spiritual support, participating in religious activities and/or spiritual practices (e.g., meditation, prayer, yoga, visiting temples), and connection with a higher power. | ✓ | ✓ |
| Substance Use – Appeal | Perceived positive aspects of substance use, including both increasing positive emotions (e.g., feeling happy and social) and alleviating negative emotions (e.g., reducing depression and anxiety). Requires a screening question to document the presence of some use: “In the past 30 days, have you used drugs other than alcohol or your prescribed medications?” | Past 30 days: ✓(18) Past 3 months: ✓(18) | Past 30 days: ✓(7) Past 3 months: ✓(7) |
| Substance Use – Prescription Pain Medication Misuse | Abuse of prescription pain medication. Requires a screening question to document the presence of a prescription for use: “In the past 3 months, did you have a prescription for pain medication?” | ✓ | ✓ |
| Substance Use – Severity | Severity of substance use in adults. Requires a screening question to document the presence of some use: “In the past 3 months, have you used drugs other than alcohol or your prescribed medications?” | Past 30 days: ✓(37) Past 3 months: ✓(37) | Past 30 days: ✓(7) Past 3 months: ✓(7) |
s This measure is a scale (items are not a subset from an item bank and the measure produces a score).
*The Medication Adherence scale is not scored using item response theory like other PROMIS measures. See its Scoring Manual for more information.
| Domain | Definition | CAT (# Items in Bank) | Short Form or Scale (# Items) |
|---|---|---|---|
| Companionship | Perceived availability of someone with whom to share enjoyable social activities such as visiting, talking, celebrations, etc. | ✓ | |
| Emotional Support | Perceived feelings of being cared for and valued as a person; having confidant relationships. | ✓ | ✓ |
| Informational Support | Perceived availability of helpful information or advice. | ✓ | ✓ |
| Instrumental Support | Perceived availability of assistance with material, cognitive or task performance. | ✓ | ✓ |
| Satisfaction with Participation in Discretionary Social Activities (v1.0) | Contentment with leisure interests and relationships with friends. | ✓ | ✓ |
| Satisfaction with Participation in Social Roles (v1.0) | Satisfaction with performing one’s usual social roles and activities. | ✓ | ✓ |
| Satisfaction with Social Roles and Activities (v2.0) | Satisfaction with performing one’s usual social roles and activities (e.g., “I am satisfied with my ability to participate in family activities”). | ✓ | ✓ |
| Social Isolation | Perceptions of being avoided, excluded, detached, disconnected from, or unknown by, others. | ✓ | ✓ |
| Domain | Definition | CAT (# Items in Bank) | Short Form or Scale (# Items) |
|---|---|---|---|
| Global Health* | Overall evaluation of one’s physical and mental health. | ✓ | |
| Global Mental | Overall evaluation of one’s mental health. | ✓ | |
| Global Physical | Overall evaluation of one’s physical health. | ✓ |
*Global Health is scored into physical and mental health summary scores.
s This measure is a scale (items are not a subset from an item bank and the measure produces a score).
| Profile Measure | Definition | CATs or Short Forms | Total Measure Length (# Items) |
|---|---|---|---|
| PROMIS-29 Profile (v2.1) | A collection of 4-item short forms assessing anxiety, depression, fatigue, pain interference, physical function, sleep disturbance, and ability to participate in social roles and activities as well as a single pain intensity item. | Short Forms | 29 |
| PROMIS-43 Profile (v2.1) | A collection of 6-item short forms assessing anxiety, depression, fatigue, pain interference, physical function, sleep disturbance, and ability to participate in social roles and activities as well as a single pain intensity item. | Short Forms | 43 |
| PROMIS-57 Profile (v2.1) | A collection of 8-item short forms assessing anxiety, depression, fatigue, pain interference, physical function, sleep disturbance, and ability to participate in social roles and activities as well as a single pain intensity item. | Short Forms | 57 |
| PROMIS-16 Profile v2.1 (PROPr) | A collection of 2-item short forms assessing Physical Function, Sleep, Pain Interference, Fatigue, Anxiety, Depression, Ability to Participate in Social Roles and Activities, and Cognitive Function—Abilities). This measure produces 8 domain scores and a PROMIS-Preference (PROPr) score. Domain scores are intended to be used as screening measures that are followed by more precise assessment or clinical inquiry. | Short Forms | 16 |
| PROMIS-29+2 Profile v2.1 (PROPr) | Consists of the PROMIS 29+2 Profile v2.1 and two (2) PROMIS Cognitive Function Abilities items. This measure was created to incorporate the PROMIS Preference Scoring System. | Short Forms | 31 |
| PROMIS Profile CAT v1.0 – 29 | A collection of 8 computer adaptive tests (CATs) assessing anxiety, depression, fatigue, pain interference, physical function, sleep disturbance, and ability to participate in social roles and activities as well as a single pain intensity item. | CATs | 29 |
| Sexual Function and Satisfaction v2.0 Brief Profile (Female) | A collection of brief (1-2) item short forms assessing participation and interest in sexual activity. Non-sexually active respondents are then asked about reasons for not participating in sexual activity, whereas sexually active respondents are then asked about orgasm, satisfaction with sex life, lubrication, and vaginal discomfort, vulvar discomfort. | Short Forms | 14 |
| Sexual Function and Satisfaction v2.0 Brief Profile (Male) | A collection of brief (1-2) item short forms assessing participation and interest in sexual activity. Non-sexually active respondents are then asked about reasons for not participating in sexual activity, whereas sexually active respondents are then asked about orgasm, satisfaction with sex life, and erectile function. | Short Forms | 10 |
| Sexual Function and Satisfaction v2.0 Brief Profile (Sexually Active Female) | A collection of brief (1-2) item short forms, intended for sexually active participants, that assesses interest in sexual activity, orgasm, satisfaction with sex life, lubrication, vaginal discomfort, and vulvar discomfort. | Short Forms | 12 |
| Sexual Function and Satisfaction v2.0 Brief Profile (Sexually Active Male) | A collection of brief (1-2) item short forms, intended for sexually active participants, that assesses interest in sexual activity, orgasm, satisfaction with sex life, and erectile function. | Short Forms | 8 |
| Sexual Function and Satisfaction v2.0 Full Profile (Female) | A collection of brief (1-4) item short forms assessing participation and interest in sexual activity. Non-sexually active respondents are then asked about reasons for not participating in sexual activity, whereas sexually active respondents are then asked about orgasm, satisfaction with sex life, lubrication, vaginal discomfort, vulvar discomfort, oral discomfort, oral dryness, and anal discomfort. | Short Forms | 26 |
| Sexual Function and Satisfaction v2.0 Full Profile (Male) | A collection of brief (1-4) item short forms assessing participation and interest in sexual activity. Non-sexually active respondents are then asked about reasons for not participating in sexual activity, whereas sexually active respondents are then asked about orgasm, satisfaction with sex life, erectile function, oral discomfort, oral dryness, and anal discomfort. | Short Forms | 20 |
| Sexual Function and Satisfaction v2.0 Full Profile (Non-Sexually Active Female) | A collection of brief (1-2) item short forms, intended for non-sexually active participants, that assesses interest and reasons for not participating in sexual activity. | Short Forms | 4 |
| Sexual Function and Satisfaction v2.0 Full Profile (Non-Sexually Active Male) | A collection of brief (1-2) item short forms, intended for non-sexually active participants, that assesses interest and reasons for not participating in sexual activity. | Short Forms | 4 |
| Sexual Function and Satisfaction v2.0 Full Profile (Sexually Active Female) | A collection of brief (1-4) item short forms, intended for sexually active participants, that assesses interest in sexual activity, orgasm, satisfaction with sex life, lubrication, vaginal discomfort, and vulvar discomfort. | Short Forms | 24 |
| Sexual Function and Satisfaction v2.0 Full Profile (Sexually Active Male) | A collection of brief (1-4) item short forms, intended for sexually active participants, that assesses interest in sexual activity, orgasm, satisfaction with sex life, and erectile function. | Short Forms | 18 |
Disease-Specific PROMIS Measures
PROMIS measures are intended to be used across patient populations. For that reason, they do not reference a specific disease or health condition (e.g., “Because of my arthritis…”). However, some PROMIS short forms were constructed by selecting a subset of items from a PROMIS item bank that are particularly relevant to individuals living with a specific health condition. Sometimes these measures added new items and co-calibrated them with the existing PROMIS item bank. These measures are collectively known as Disease-Specific PROMIS Measures.
Deciding when to use a disease-specific measure versus a general PROMIS measure is nuanced. See Recommended Measures for our guidance on what measures to use when working with specific patient populations.
| Measure Name | Domain | Definition | # Items |
|---|---|---|---|
| PROMIS – Cancer Bank v1.0 – Anxiety | Anxiety | Measures respondents’ self-reported symptoms of anxiety in the context of cancer and/or cancer treatment experiences. | 22 (20 PROMIS items + 2 new items) |
| PROMIS – Cancer Bank v1.0 – Depression | Depression | Measures respondents’ self-reported symptoms of depression in the context of cancer and/or cancer treatment experiences. | 30 (23 PROMIS items + 7 new items) |
| PROMIS – Cancer Bank v1.0 – Fatigue | Fatigue | Measures self-reported symptoms of tiredness and exhaustion in the context of cancer and/or cancer treatment experiences. | 54 (all PROMIS items) |
| PROMIS – Cancer Bank v1.1 – Pain Interference | Pain Interference | Measures self-reported consequences of pain on relevant aspects of one’s life, in this case, in the context of cancer and/or cancer treatment experiences. | 35 (32 PROMIS items + 3 new items) |
| PROMIS – Cancer Bank v1.1 – Physical Function | Physical Function | Measures respondents’ self-reported capability to physically function in the context of cancer and/or cancer treatment experiences. | 45 (33 PROMIS items + 12 new items) |
| PROMIS Short Form v2.0 – Physical Function 10b | Physical Function | Measures respondents’ self-reported capability to physically function in the context of cancer and/or cancer treatment experiences. | 10 (all PROMIS items) |
| PROMIS Short Form v2.0 – Physical Function 8c | Physical Function | Measures respondents’ self-reported capability to physically function in the context of cancer and/or cancer treatment experiences. Items selected in collaboration with FDA. | 10 (all PROMIS items) |
| PROMIS Short Form v2.0 – Physical Function 8c | Physical Function | Measures respondents’ self-reported capability to physically function in the context of cancer and/or cancer treatment experiences. Items selected in collaboration with FDA. | 8 (all PROMIS items) |
| PROMIS Short Form v2.0 – Physical Function 8c 7-day | Physical Function | Measures respondents’ self-reported capability to physically function in the context of cancer and/or cancer treatment experiences. Uses a 7-day recall period. Items selected in collaboration with FDA. | 8 (all PROMIS items) |
| PROMIS+Heart Failure-27 Profile v1.0 | Multiple | Measures disease-specific physical health, mental health, social health, and overall health among patients with heart failure; the 27-item Profile was developed primarily for research purposes. | 27 (17 PROMIS items + 10 new items) |
| PROMIS+Heart Failure-10 Profile v1.0 | Multiple | Measures disease-specific physical health, mental health, social health, and overall health among patients with heart failure; the 10-item Profile was developed primarily for clinical purposes. | 10 (6 PROMIS items + 4 new items) |
| PROMIS Short Form v1.0 – Fatigue – Multiple Sclerosis 8a | Fatigue | Measures the experience and impacts of fatigue in adults with multiple sclerosis. | 8 (all PROMIS items) |
| PROMISnq Short Form v2.0 – Physical Function–Multiple Sclerosis 15a | Physical Function | Measures adult respondents’ self-reported capability to physically function in the context of multiple sclerosis. | 15 (12 PROMIS items + 2 Neuro-QoL items + 1 new item) |
| PROMIS Short Form v2.0 – Ability to Participate in Social Roles and Activities–OA-Knee 8a | Ability to Participate in Social Roles and Activities | Measures self-reported ability to perform one’s usual social roles and activities. Items assess disease-specific issues but do not reference knee arthritis. | 8 (all PROMIS items) |
| PROMIS Short Form v1.0 – Depression–OA-Knee 4a | Depression | Measures self-reported symptoms of depression. Items assess disease-specific issues but do not reference knee arthritis. | 4 (all PROMIS items) |
| PROMIS Short Form v1.0 – Fatigue-OA-Knee 8a | Fatigue | Measures self-reported symptoms of tiredness and exhaustion. Items assess disease-specific issues but do not reference knee arthritis. | 8 (all PROMIS items) |
| PROMIS+OA-Knee Short Form v1.1 – Pain Interference 13a | Pain Interference | Measures self-reported consequences of pain on relevant aspects of one’s life. New items reference knee pain. | 13 (8 PROMIS items + 5 new items) |
| PROMIS+OA-Knee Short Form v2.0 – Physical Function 13a | Physical Function | Measures self-reported capability to function physically. New items reference the knee or assistive devices. | 13 (8 PROMIS items + 5 new items) |
| PROMIS+OA-Knee Short Form v2.0 – Satisfaction with Social Roles and Activities 9a | Satisfaction with Social Roles and Activities | Measures self-reported satisfaction with performing one’s usual social roles and activities. Items assess disease-specific issues but do not reference knee arthritis. | 9 (8 PROMIS items + 1 new items) |
| PROMIS Short Form v1.0 – Sleep Disturbance–OA-Knee 6a | Sleep Disturbance | Measures self-reported sleep quality, sleep depth, and restoration associated with sleep in the context of osteoarthritis of the knee. | 6 (all PROMIS items) |
| PROMIS Short Form v2.0 – Social Isolation–OA-Knee 2a | Social Isolation | Measures self-reported social distance from other individuals. Items assess disease-specific issues but do not reference knee arthritis. | 2 (all PROMIS items) |
| PROMIS Pools v1.0 – OA-Knee | Multiple | A collection of six PROMIS OA-Knee item pools assess self-reported Anger, Anxiety, Independence, Life Satisfaction, Pain Intensity, and Symptoms in the context of osteoarthritis of the knee. | 13 (split across 6 item pools) |
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Last updated: September 14, 2026